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  • ACTN4抗原(重組蛋白)

    規(guī)格:
    • 品牌 : 通蔚生物
    • 目錄號 : TW15738
    • 應(yīng)用 : 僅供科研使用
    • 貨期 : 現(xiàn)貨
    • 規(guī)格 :1mg/100ug
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中文名稱:ACTN4抗原(重組蛋白)

英文名稱: ACTN4 Antigen (Recombinant Protein)

別      名: FSGS; FSGS1; ACTININ-4

儲      存: 冷凍(-20℃)

相關(guān)類別: 抗原

概  述:

Fusion protein corresponding to a region derived from 50-269 amino acids of human ACTN4


技術(shù)規(guī)格:

Full name:

actinin, alpha 4

Synonyms:

FSGS; FSGS1; ACTININ-4

Swissprot:

O43707

Gene Accession:

BC005033

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes.



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