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  • ANLN 抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW15940
    • 應(yīng)用 : 僅限于科研使用
    • 貨期 : 現(xiàn)貨
    • 規(guī)格 :100ug
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中文名稱ANLN 抗原(重組蛋白)

英文名稱: ANLN Antigen (Recombinant Protein)

別      名: anillin, actin binding protein; scra; Scraps

儲      存: 冷凍(-20℃)

相關(guān)類別: 抗原

概  述:

Fusion protein corresponding to a region derived from C terminal 300 amino acids of human ANLN


技術(shù)規(guī)格:

Full name:

anillin, actin binding protein

Synonyms:

scra; Scraps

Swissprot:

Q9NQW6

Gene Accession:

BC034692

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

?Anillin, also known as scraps homolog, is an evolutionarily conserved Actin- binding protein required for cytokinesis that was first identified in Drosophila melanogaster. Anillin is a ubiquitously expressed protein with highest expression levels in the central nervous system. It is predominantly found in the nucleus and it localizes to the cleavage furrow during cytokinesis, forming a ring with the help of Rac GTPase. During cytokinesis, Anillin interacts with CD2AP and functions to concentrate Rho A and maintain the localization of active Myosin. In Anillin knockout cells the cleavage furrow fails to complete ingression. Anillin expression levels fluctuate with the cell cycle, peaking in mitosis.


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